This course will introduce students to the amazing molecules that make life possible, how they work individually (I Structure & Function) and how they form nanomachines and networks to do the essential life processes of harnessing energy (II) and self-replication (III). Chemists and biochemists use a full range of chemical principles to unravel the mechanisms of these processes and to use these insights to engineer large and small molecules for applications in medicine and biotechnology (IV).
This course assumes a strong background in chemistry and does not require a background in biology.
General schedule (detailed, yet dynamic, schedule found on course website):
- Structure & Function; 1/20 – 2/24
Exam 1 (in class); 2/26
- Harnessing Energy; 3/1 – 3/29
Exam 2 (in class); 3/31
- Self-Replication; 4/2 – 4/21
Exam 3 (in class); 4/24
- Engineering Molecules; 4/26 – 4/30
Final exam (in class); 5/3
Course website can be found at: http://www.chamberslab.com then click on “Chem 423”
Instructor: James Chambers, LGRT 602, chambers at chem. umass. edu
Office hours: Tuesdays at 9 – 10
Required text: Biochemistry, 6th ed., 2007, by Berg, Tymoczko, Stryer (WH Freeman & Co).
Prerequisite: One year of organic chemistry.
20% each for 3 exams
25% final exam
5% class participation
Advance notice and legitimate reasons required for makeup exams or quizzes.